U.S. stocks lower at close of trade; Dow Jones Industrial Average down 0.40%

Investing.com – U.S. stocks were lower after the close on Wednesday, as losses in the , and sectors led shares lower.

At the close in NYSE, the fell 0.40%, while the index declined 0.38%, and the index lost 0.51%.

The best performers of the session on the were Boeing Co (NYSE:), which rose 1.07% or 3.91 points to trade at 370.91 at the close. Meanwhile, Johnson & Johnson (NYSE:) added 0.83% or 1.12 points to end at 135.94 and Chevron Corp (NYSE:) was up 0.76% or 0.89 points to 117.34 in late trade.

The worst performers of the session were Home Depot Inc (NYSE:), which fell 2.20% or 4.96 points to trade at 220.90 at the close. 3M Company (NYSE:) declined 1.70% or 2.91 points to end at 167.77 and Pfizer Inc (NYSE:) was down 1.62% or 0.61 points to 37.05.

The top performers on the S&P 500 were Target Corporation (NYSE:) which rose 14.05% to 126.43, Nektar Therapeutics (NASDAQ:) which was up 8.85% to settle at 19.93 and Schlumberger NV (NYSE:) which gained 5.33% to close at 36.14.

The worst performers were L Brands Inc (NYSE:) which was down 7.51% to 15.89 in late trade, Nordstrom Inc (NYSE:) which lost 4.37% to settle at 33.95 and Capri Holdings Ltd (NYSE:) which was down 3.64% to 35.19 at the close.

The top performers on the NASDAQ Composite were Cancer Genetics Inc (NASDAQ:) which rose 131.25% to 4.810, Kazia Therapeutics Ltd ADR (NASDAQ:) which was up 130.16% to settle at 7.400 and Diffusion Pharmaceuticals Inc (NASDAQ:) which gained 67.59% to close at 0.3687.

The worst performers were Genprex Inc (NASDAQ:) which was down 43.55% to 0.3500 in late trade, CTI Industries Corporation (NASDAQ:) which lost 26.88% to settle at 0.51 and Professional Diversity Network Inc (NASDAQ:) which was down 25.68% to 0.9068 at the close.

Falling stocks outnumbered advancing ones on the New York Stock Exchange by 1633 to 1190 and 108 ended unchanged; on the Nasdaq Stock Exchange, 1676 fell and 983 advanced, while 77 ended unchanged.

Shares in Target Corporation (NYSE:) rose to all time highs; up 14.05% or 15.58 to 126.43. Shares in Genprex Inc (NASDAQ:) fell to all time lows; down 43.55% or 0.2700 to 0.3500. Shares in Kazia Therapeutics Ltd ADR (NASDAQ:) rose to 3-years highs; up 130.16% or 4.185 to 7.400. Shares in CTI Industries Corporation (NASDAQ:) fell to all time lows; down 26.88% or 0.19 to 0.51.

The , which measures the implied volatility of S&P 500 options, was down 0.62% to 12.78.

Gold Futures for December delivery was down 0.17% or 2.45 to $1471.85 a troy ounce. Elsewhere in commodities trading, Crude oil for delivery in January rose 3.14% or 1.74 to hit $57.09 a barrel, while the January Brent oil contract rose 2.53% or 1.54 to trade at $62.45 a barrel.

EUR/USD was up 0.03% to 1.1076, while USD/JPY fell 0.06% to 108.53.

The US Dollar Index Futures was up 0.06% at 97.797.

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